Ryanodine receptor-2 upregulation and nicotine-mediated plasticity
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چکیده
منابع مشابه
Ryanodine receptor-2 upregulation and nicotine-mediated plasticity.
Nicotine, the major psychoactive component of cigarette smoke, modulates neuronal activity to produce Ca2+-dependent changes in gene transcription. However, the downstream targets that underlie the long-term effects of nicotine on neuronal function, and hence behaviour, remain to be elucidated. Here, we demonstrate that nicotine administration to mice upregulates levels of the type 2 ryanodine ...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2010
ISSN: 0261-4189
DOI: 10.1038/emboj.2010.279